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602 datasets from 5 repositories. Filter by the analysis you need to run, not by what a repository says a dataset contains. How capability is measured.
15 of 602 datasets
- Foundation Medicine Adult Cancer Clinical Dataset (FM-AD)Underused opportunityMixedProject-curated
18,004 patients profiled with a targeted clinical panel - the largest cohort in the Genomic Data Commons, with no informative vital status, no race data, and no treatment records.
Clinical dataTargeted DNA panel - Molecular Profiling to Predict Response to Treatment for Acute Lymphoblastic LeukemiaUnderused opportunityMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 8.3 years; 6 measurement types on the same cohort
1,510 children with acute lymphoblastic leukaemia from Children's Oncology Group trials, with whole genome sequencing, 8.4 years of median follow-up, and a named treatment regimen and response recorded for every single case.
Clinical dataCopy numberBulk RNA sequencingStructural variantsWhole genome sequencingWhole exome sequencing - Breast Invasive CarcinomaMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 2.3 years; 12 measurement types on the same cohort
1,098 breast tumors measured twelve ways across GDC and IDC, with treatment outcome on 64% of cases - the most reused dataset in this corpus and still the reference cohort for method development.
ATAC sequencingClinical dataCopy numberHistopathology slidesDNA methylationmicroRNA+6 more - NCI Cancer Model Development for the Human Cancer Model InitiativeUnderused opportunityMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 15.8 months; 10 measurement types on the same cohort
805 next-generation cancer models - organoids and other patient-derived systems - with whole genome sequencing on 804 and the matched patient tumor, spanning many rare cancers.
Clinical dataCopy numberHistopathology slidesDNA methylationmicroRNARadiology imaging+4 more - Glioblastoma MultiformeMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 12.0 months; 12 measurement types on the same cohort
617 glioblastomas with twelve measurement types including radiology on 607 and pathology slides on 389 - the reference glioma cohort, with a median follow-up of 12.0 months.
ATAC sequencingClinical dataCopy numberHistopathology slidesDNA methylationmicroRNA+6 more - Comprehensive genomic characterization of radiation-related papillary thyroid cancer in the UkraineMixedProject-curated
Why it fits: 5 measurement types on the same cohort
449 papillary thyroid carcinomas from Ukrainians exposed to Chernobyl fallout as children - an irreplaceable radiation-exposure cohort with essentially no clinical annotation and no usable outcome data at all.
Copy numbermicroRNABulk RNA sequencingStructural variantsWhole genome sequencing - HIV+ Tumor Molecular Characterization Project - Cervical CancerMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 13.2 months; 10 measurement types on the same cohort
212 cervical carcinomas from Ugandan women, 98% Black African and enriched for HIV infection - the largest genomically characterized cervical cancer cohort from sub-Saharan Africa, with ECOG status on 99% of cases, treatment outcome on 68%, and a derivable follow-up time for every single case.
Clinical dataCopy numberHistopathology slidesDNA methylationmicroRNARadiology imaging+4 more - NSCLC RadiogenomicsUnderused opportunityOpenProject-curated
Why it fits: 3 measurement types on the same cohort; no access request needed
211 non-small cell lung cancers with pre-surgical CT and PET/CT, semantic annotations, segmentations and matched gene expression - a genuinely paired imaging-genomics cohort, fully open, and described only in prose.
Clinical dataRadiology imagingWhole genome sequencing - CPTAC STAD StudyUnderused opportunityOpenProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 2.0 years; 7 measurement types on the same cohort
193 gastric cancers measured seven ways - proteome, phosphoproteome, acetylome, glycoproteome, ubiquitylome, metabolome and protein-protein interaction - the deepest single-cohort molecular characterization in the NCI portfolio, and openly downloadable.
AcetylomeGlycoproteomeMetabolomeOtherPhosphoproteomeProteome (mass spectrometry)+1 more - CPTAC AML StudyOpenProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 12.1 months; 6 measurement types on the same cohort
164 acute myeloid leukaemias with proteome, phosphoproteome, acetylome and glycoproteome, plus lipidomics and metabolomics on 98 - one of only three NCI cohorts carrying lipidomic data, openly downloadable.
AcetylomeGlycoproteomeLipidomeMetabolomePhosphoproteomeProteome (mass spectrometry) - The Cellular Geography of Therapeutic Resistance in CancerMixedProject-curated
Why it fits: 3 measurement types on the same cohort; scarce measurements: Multiplexed tissue imaging
An HTAN atlas built explicitly around therapeutic resistance, with multiplexed imaging, single-cell RNA sequencing and the richest clinical annotation of any atlas here - and no publications recorded in the network's own manifest.
Bulk DNA sequencingSingle-cell RNA sequencingMultiplexed tissue imaging - CPTAC LUAD Discovery StudyOpenProject-curated
Why it fits: survival endpoints, median follow-up 15.7 months; 4 measurement types on the same cohort; scarce measurements: Acetylome, Ubiquitylome
115 lung adenocarcinomas with proteome, phosphoproteome and acetylome, plus ubiquitylome on 80 - one of five ubiquitylation datasets in the Proteomic Data Commons, openly downloadable.
AcetylomePhosphoproteomeProteome (mass spectrometry)Ubiquitylome - Genomic Characterization of Metastatic Castration Resistant Prostate CancerMixedProject-curated
Why it fits: survival endpoints, median follow-up 7.9 years; 4 measurement types on the same cohort
101 metastatic castration-resistant prostate cancers with whole genome and RNA sequencing from metastatic biopsies - every case stage IV with documented progression, and no usable vital status.
Copy numberBulk RNA sequencingStructural variantsWhole genome sequencing - HIV+ Tumor Molecular Characterization Project - Diffuse Large B-Cell LymphomaMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 11.3 months; 8 measurement types on the same cohort
70 diffuse large B-cell lymphomas from an HIV-enriched cohort, half Black or African American, with whole genome sequencing on 66 and named chemotherapy regimens on a quarter.
Clinical dataCopy numberHistopathology slidesmicroRNARadiology imagingBulk RNA sequencing+2 more - HIV+ Tumor Molecular Characterization Project - Lung CancerMixedProject-curated
Why it fits: treatment response recorded; survival endpoints, median follow-up 6.4 months; 8 measurement types on the same cohort
39 lung cancers from an HIV-enriched cohort, two thirds Black or African American, with whole genome sequencing on every case and clinical staging on 62% - very small, and addressing a population that appears in almost no lung cancer genomics.
Clinical dataCopy numberHistopathology slidesmicroRNARadiology imagingBulk RNA sequencing+2 more