{"id":"gdc-tcga-thym","title":"Thymoma","short_title":"TCGA-THYM","aliases":["tcga_thym"],"summary":"This cancer develops in the outer surface of the thymus, a gland behind the breastbone that produces T-cells, a type of white blood cells. Thymoma is rare, but it is the most common tumor in adults affecting the mediastinum, which is the cavity between the lungs containing the heart, esophagus, and trachea. A tumor of the thymus tends to grow slowly and rarely spreads to other parts of the body. However, of the estimated 400 Americans who develop this cancer each year, half are diagnosed with metastatic thymoma. When the cancer metastasizes, only 45% of patients survive five years after their diagnosis. 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Please see the DICOM converted Slide Microscopy images for the TCGA-THYM collection page to learn more about the histopathology images and to obtain any supporting metadata for th","locator":"accession extracted from description prose","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Cross-repository link recovered from prose; verify before relying on it."}]}],"repository":{"name":"NCI Genomic Data Commons","short_name":"GDC","url":"https://portal.gdc.cancer.gov","is_nci_crdc_node":true,"is_nih_repository":true},"additional_repositories":[{"name":"NCI Imaging Data 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Every dataset is measured with the same single section field per tier, so the counts are comparable; the per-tier value is the largest across the dataset's own accessions, excluding any accession shared with other datasets in the corpus. 30 of 30 sampled open-access articles contain the literal accession TCGA-THYM; the rest match only because Europe PMC indexes the hyphen as a word break. Counts for this dataset are scaled by 100% accordingly."},{"method":"derived","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search","source_label":"Europe PMC first-reference dating","retrieved_at":"2026-09-20T18:13:53.528952Z","snippet":null,"locator":"first referenced in 2018 (METHODS section)","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Availability dated from the literature (epmc-first-reference-v2) rather than from repository file timestamps, which record re-harmonization. This is a lower bound on availability."}]},"underexplored":{"is_underexplored":false,"basis":["Reuse is within the expected range for comparable datasets (index -0.71)."],"index_value":-0.706,"percentile":31.8,"comparator_set":"132 datasets in this corpus with a citable accession and sufficient metadata","evidence":[{"method":"derived","source_url":null,"source_label":"Reuse Gap Index (rgi-huber-v2)","retrieved_at":"2026-09-21T02:11:22.976067Z","snippet":null,"locator":"Huber robust regression of log2(analyzing articles + 1) on cohort size, years available, modality breadth and access tier","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Model, covariates and coefficients are published with the dataset export so the label can be recomputed or contested."}]},"grants":[{"core_project_num":"U24CA211000","project_num":null,"title":"Pathway and Network Integration of Cancer Genomics and Clinical Data","pi_names":["Benjamin Raphael","Jen Jen Yeh"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2016,2017,2018,2019,2020],"award_amount_usd":1678218,"org_name":"PRINCETON UNIVERSITY","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA211000","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA211000","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA211000","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA210999","project_num":null,"title":"Global Infrastructure for Collaborative High-throughput  Cancer Genomics Analysis","pi_names":["GAD A GETZ"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2016,2017,2018,2019,2020],"award_amount_usd":4656218,"org_name":"BROAD INSTITUTE, INC.","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA210999","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA210999","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA210999","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA210990","project_num":null,"title":"UCSC-Buck Specialized Genomic Data Analysis Center for the Genomic Data Analysis Network","pi_names":["JOSHUA Michael STUART"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2016,2017,2018,2019,2020],"award_amount_usd":2181795,"org_name":"UNIVERSITY OF CALIFORNIA SANTA CRUZ","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA210990","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA210990","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA210990","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA210957","project_num":null,"title":"OHSU Center for Specialized Data Analysis as part of the GDAN","pi_names":["Emek Demir","PAUL T. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA210950","project_num":null,"title":"Integrated analysis of protein expression data from the Reverse Phase Protein Array (RPPA) platform","pi_names":["Rehan Akbani","GORDON B. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA210949","project_num":null,"title":"Batch effects in molecular profiling data on cancers: detection, quantitation, interpretation, and correction","pi_names":["Rehan Akbani","GORDON B. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA144025","project_num":null,"title":"Harvard Genome Characterization Center","pi_names":["Raju S. Kucherlapati"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":13968228,"org_name":"BRIGHAM AND WOMEN'S HOSPITAL","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA144025","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA144025","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA144025","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143883","project_num":null,"title":"Integrative Pipeline for Analysis & Translational Application of TCGA Data (GDAC)","pi_names":["Rehan Akbani","GORDON B. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143882","project_num":null,"title":"The USC-JHU Cancer Epigenome Characterization Center","pi_names":["STEPHEN B. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143867","project_num":null,"title":"Genome Characterization Center (GCC)","pi_names":["Stacey Gabriel","Matthew L. 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Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143866","project_num":null,"title":"Cancer transcriptome characterization using massively parallel DNA sequencing","pi_names":["Marco Antonio Marra"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2015],"award_amount_usd":10876224,"org_name":"BRITISH COLUMBIA CANCER AGENCY","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143866","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA143866","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA143866","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143848","project_num":null,"title":"Gene Expression Patterns in Human Tumors Identified Using Transcript Sequencing","pi_names":["David N Hayes","CHARLES M PEROU"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":20842970,"org_name":"UNIV OF NORTH CAROLINA CHAPEL HILL","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143848","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA143848","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA143848","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143845","project_num":null,"title":"The Cancer Genome Atlas Data Analysis Center","pi_names":["LYNDA CHIN","GAD A GETZ"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":15987999,"org_name":"BROAD INSTITUTE, INC.","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143845","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA143845","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA143845","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143843","project_num":null,"title":"The BCM Tumor Genome Characterization Center","pi_names":["RICHARD A GIBBS","David Andrew Wheeler"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013],"award_amount_usd":9488061,"org_name":"BAYLOR COLLEGE OF MEDICINE","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143843","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA143843","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA143843","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143840","project_num":null,"title":"MSKCC Center for Translational Cancer Genomic Analysis","pi_names":["Marc Ladanyi","CHRIS SANDER"],"agency_ic":"NCI","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":11508790,"org_name":"SLOAN-KETTERING INST CAN RESEARCH","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143840","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-18T03:25:21.369163Z","snippet":null,"locator":"PMID 29438696 reported under U24CA143840","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Funding role inferred from whether the award appears on the dataset's own publication or on a downstream study."},{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 29438696 (this dataset's marker paper) reported under U24CA143840","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. 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