{"id":"gdc-tcga-blca","title":"Bladder Urothelial Carcinoma","short_title":"TCGA-BLCA","aliases":["tcga_blca"],"summary":"The Cancer Genome Atlas-Bladder Endothelial Carcinoma (TCGA-BLCA) data collection is part of a larger effort to enhance the TCGA http://cancergenome.nih.gov/ data set with characterized radiological images. The Cancer Imaging Program (CIP), with the cooperation of several of the TCGA tissue-contributing institutions, has archived a large portion of the radiological images of the genetically-analyzed BLCA cases. Please see the TCGA-BLCA page to learn more about the radiology images and to obtain any supporting metadata for this collection. Please see the DICOM converted Slide Microscopy images for the TCGA-BLCA collection page to learn more about the histopathology images and to obtain any supporting metadata for this collection.","one_liner":null,"identifiers":[{"scheme":"gdc_project_id","value":"TCGA-BLCA","url":"https://portal.gdc.cancer.gov/projects/TCGA-BLCA","is_primary":true,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"scheme":"gdc_program","value":"TCGA","url":null,"is_primary":false,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"scheme":"dbgap_phs","value":"phs000178","url":"https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000178","is_primary":false,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"scheme":"idc_collection_id","value":"tcga_blca","url":"https://portal.imaging.datacommons.cancer.gov/explore/?collection_id=tcga_blca","is_primary":true,"evidence":[{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"scheme":"tcia_collection","value":"TCGA-BLCA","url":"https://www.cancerimagingarchive.net/collections/","is_primary":false,"evidence":[{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"scheme":"doi","value":"10.7937/K9/TCIA.2016.8LNG8XDR","url":null,"is_primary":false,"evidence":[{"method":"fulltext","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC collection description","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":"ge portion of the radiological images of the genetically-analyzed BLCA cases. Please see the TCGA-BLCA page to learn more about the radiology images and to obtain any supporting metadata for t","locator":"accession extracted from description prose","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Cross-repository link recovered from prose; verify before relying on it."}]},{"scheme":"zenodo","value":"10.5281/zenodo.12690045","url":null,"is_primary":false,"evidence":[{"method":"fulltext","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC collection description","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":"r this collection. Please see the DICOM converted Slide Microscopy images for the TCGA-BLCA collection page to learn more about the histopathology images and to obtain any supporting metadata for th","locator":"accession extracted from description prose","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Cross-repository link recovered from prose; verify before relying on it."}]}],"repository":{"name":"NCI Genomic Data Commons","short_name":"GDC","url":"https://portal.gdc.cancer.gov","is_nci_crdc_node":true,"is_nih_repository":true},"additional_repositories":[{"name":"NCI Imaging Data Commons","short_name":"IDC","url":"https://portal.imaging.datacommons.cancer.gov","is_nci_crdc_node":true,"is_nih_repository":true}],"program_name":"TCGA","program_url":"https://portal.gdc.cancer.gov/analysis_page?app=Projects","nci_program":"TCGA","generating_institutions":[],"data_generation_funding_role":"generation","version":null,"release_date":"2014-01-01","last_upstream_update":null,"retrieved_at":"2026-09-18T02:36:30.246561Z","landing_page_url":"https://portal.gdc.cancer.gov/projects/TCGA-BLCA","cancer_types":[{"label":"Epithelial Neoplasms, NOS","ontology":null,"code":null,"url":null},{"label":"Adenomas and Adenocarcinomas","ontology":null,"code":null,"url":null},{"label":"Squamous Cell Neoplasms","ontology":null,"code":null,"url":null},{"label":"Transitional Cell Papillomas and Carcinomas","ontology":null,"code":null,"url":null}],"primary_sites":["Bladder"],"subject":{"scope":"single","tissues":["BLADDER"],"evidence":[{"method":"derived","source_url":null,"source_label":"cds.subjects","retrieved_at":null,"snippet":null,"locator":"cancer_types: Epithelial Neoplasms, NOS, Adenomas and Adenocarcinomas, Squamous Cell Neoplasms, Transitional Cell Papillomas and Carcinomas; primary_sites: Bladder","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Repository disease labels or primary sites mapped to pinned tissues."}]},"is_pediatric":null,"model_systems":[],"cohort":{"n_cases":412,"n_samples":null,"n_aliquots":null,"n_files":31502,"total_bytes":411323757738156,"n_tumor_cases":null,"n_normal_cases":null,"has_matched_normal":null,"demographics":{"sex":{"male":304,"female":108},"race":{"white":327,"asian":44,"black or african american":23,"not reported":11,"unknown":7},"ethnicity":{"not hispanic or latino":371,"not reported":30,"hispanic or latino":9,"unknown":2},"age_at_diagnosis_years":{"n":411.0,"min":34.4,"q1":60.8,"median":69.2,"q3":76.7,"max":90.0},"vital_status":{"alive":230,"dead":182},"country_or_region":{"united states":298,"vietnam":36,"united kingdom":32,"brazil":16,"germany":7,"netherlands":6,"canada":4,"romania":4,"puerto rico":2,"ukraine":2,"russia":1},"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"demographic.*","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null},{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},"assays":[{"modality":"wxs","label":"Whole exome sequencing","platform":"illumina","n_cases":412,"n_samples":null,"n_files":6708,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"copy_number","label":"SNP genotyping array (copy number, germline)","platform":"illumina","n_cases":412,"n_samples":null,"n_files":5297,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"methylation","label":"DNA methylation array","platform":"illumina","n_cases":412,"n_samples":null,"n_files":1320,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"histopathology","label":"Whole-slide tissue images","platform":"illumina","n_cases":412,"n_samples":null,"n_files":469,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null},{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":"field: supporting_data","confidence":"medium","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"clinical","label":"Clinical","platform":null,"n_cases":412,"n_samples":null,"n_files":994,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null},{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":"field: supporting_data","confidence":"medium","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"radiology","label":"DICOM medical imaging","platform":null,"n_cases":412,"n_samples":null,"n_files":null,"data_levels":["DICOM series"],"access_tier":"open","evidence":[{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"wgs","label":"Whole genome sequencing","platform":"illumina","n_cases":411,"n_samples":null,"n_files":9881,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null},{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":"field: supporting_data","confidence":"medium","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"mirna","label":"microRNA sequencing","platform":"illumina","n_cases":409,"n_samples":null,"n_files":1311,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"rna_seq","label":"Bulk RNA sequencing","platform":"illumina","n_cases":406,"n_samples":null,"n_files":3878,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"structural_variant","label":"Somatic Structural Variation","platform":null,"n_cases":402,"n_samples":null,"n_files":2286,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"protein_array","label":"Reverse phase protein array","platform":"illumina","n_cases":343,"n_samples":null,"n_files":343,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"modality":"atac_seq","label":"ATAC sequencing (chromatin accessibility)","platform":"illumina","n_cases":10,"n_samples":null,"n_files":10,"data_levels":[],"access_tier":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/TCGA-BLCA?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API /projects","retrieved_at":"2026-09-18T02:32:25.909822Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]}],"clinical_variables":[{"name":"demographic.sex_at_birth","harmonized_name":"demographic.sex_at_birth","label":"Sex at birth","category":"demographic","n_nonmissing":412,"n_not_reported":0,"n_informative":412,"n_total":412,"coverage_pct":100.0,"populated_pct":100.0,"is_repeated":false,"example_values":["male","female"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.sex_at_birth","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.race","harmonized_name":"demographic.race","label":"Race","category":"demographic","n_nonmissing":412,"n_not_reported":18,"n_informative":394,"n_total":412,"coverage_pct":95.6,"populated_pct":100.0,"is_repeated":false,"example_values":["white","asian","black or african american","not reported","unknown"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.race","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.ethnicity","harmonized_name":"demographic.ethnicity","label":"Ethnicity","category":"demographic","n_nonmissing":412,"n_not_reported":32,"n_informative":380,"n_total":412,"coverage_pct":92.2,"populated_pct":100.0,"is_repeated":false,"example_values":["not hispanic or latino","not reported","hispanic or latino","unknown"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.ethnicity","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.vital_status","harmonized_name":"demographic.vital_status","label":"Vital status","category":"outcome","n_nonmissing":412,"n_not_reported":0,"n_informative":412,"n_total":412,"coverage_pct":100.0,"populated_pct":100.0,"is_repeated":false,"example_values":["alive","dead"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.vital_status","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.cause_of_death","harmonized_name":"demographic.cause_of_death","label":"Cause of death","category":"outcome","n_nonmissing":0,"n_not_reported":0,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.0,"is_repeated":false,"example_values":[],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.cause_of_death","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.population_group","harmonized_name":"demographic.population_group","label":"Population group","category":"demographic","n_nonmissing":0,"n_not_reported":0,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.0,"is_repeated":false,"example_values":[],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.population_group","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"demographic.country_of_residence_at_enrollment","harmonized_name":"demographic.country_of_residence_at_enrollment","label":"Country of residence","category":"demographic","n_nonmissing":408,"n_not_reported":0,"n_informative":408,"n_total":412,"coverage_pct":99.0,"populated_pct":99.0,"is_repeated":false,"example_values":["united states","vietnam","united kingdom","brazil","germany","netherlands"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: demographic.country_of_residence_at_enrollment","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.primary_diagnosis","harmonized_name":"diagnoses.primary_diagnosis","label":"Primary diagnosis","category":"diagnosis","n_nonmissing":412,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":100.0,"is_repeated":true,"example_values":["transitional cell carcinoma","adenocarcinoma, nos","carcinoma, nos","papillary transitional cell carcinoma","papillary transitional cell carcinoma, non-invasive","not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.primary_diagnosis (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.morphology","harmonized_name":"diagnoses.morphology","label":"Morphology (ICD-O)","category":"pathology","n_nonmissing":412,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":100.0,"is_repeated":true,"example_values":["8120/3","not reported","8140/3","8130/3","8070/3","8090/3"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.morphology (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.tissue_or_organ_of_origin","harmonized_name":"diagnoses.tissue_or_organ_of_origin","label":"Tissue or organ of origin","category":"diagnosis","n_nonmissing":412,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":100.0,"is_repeated":true,"example_values":["bladder, nos","prostate gland","lateral wall of bladder","posterior wall of bladder","lung, nos","bone, nos"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.tissue_or_organ_of_origin (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.ajcc_pathologic_stage","harmonized_name":"diagnoses.ajcc_pathologic_stage","label":"AJCC pathologic stage","category":"staging","n_nonmissing":410,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":99.5,"is_repeated":true,"example_values":["stage ii","stage iii","stage iv","stage i","stage iia","stage iib"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.ajcc_pathologic_stage (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.ajcc_clinical_stage","harmonized_name":"diagnoses.ajcc_clinical_stage","label":"AJCC clinical stage","category":"staging","n_nonmissing":0,"n_not_reported":0,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.0,"is_repeated":false,"example_values":[],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.ajcc_clinical_stage","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.tumor_grade","harmonized_name":"diagnoses.tumor_grade","label":"Tumor grade","category":"pathology","n_nonmissing":412,"n_not_reported":4,"n_informative":408,"n_total":412,"coverage_pct":99.0,"populated_pct":100.0,"is_repeated":false,"example_values":["high grade","low grade","unknown","not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.tumor_grade","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.prior_treatment","harmonized_name":"diagnoses.prior_treatment","label":"Prior treatment","category":"treatment","n_nonmissing":412,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":100.0,"is_repeated":true,"example_values":["no","yes"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.prior_treatment (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.prior_malignancy","harmonized_name":"diagnoses.prior_malignancy","label":"Prior malignancy","category":"diagnosis","n_nonmissing":412,"n_not_reported":3,"n_informative":409,"n_total":412,"coverage_pct":99.3,"populated_pct":100.0,"is_repeated":false,"example_values":["no","yes","not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.prior_malignancy","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.synchronous_malignancy","harmonized_name":"diagnoses.synchronous_malignancy","label":"Synchronous malignancy","category":"diagnosis","n_nonmissing":412,"n_not_reported":1,"n_informative":411,"n_total":412,"coverage_pct":99.8,"populated_pct":100.0,"is_repeated":false,"example_values":["no","yes","not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.synchronous_malignancy","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.progression_or_recurrence","harmonized_name":"diagnoses.progression_or_recurrence","label":"Progression or recurrence","category":"outcome","n_nonmissing":1,"n_not_reported":1,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.2,"is_repeated":false,"example_values":["not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.progression_or_recurrence","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.last_known_disease_status","harmonized_name":"diagnoses.last_known_disease_status","label":"Last known disease status","category":"outcome","n_nonmissing":1,"n_not_reported":1,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.2,"is_repeated":false,"example_values":["not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.last_known_disease_status","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.classification_of_tumor","harmonized_name":"diagnoses.classification_of_tumor","label":"Classification of tumor","category":"pathology","n_nonmissing":412,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":100.0,"is_repeated":true,"example_values":["primary","metastasis","prior primary","synchronous primary","recurrence","subsequent primary"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.classification_of_tumor (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.treatments.treatment_type","harmonized_name":"diagnoses.treatments.treatment_type","label":"Treatment type","category":"treatment","n_nonmissing":408,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":99.0,"is_repeated":true,"example_values":["radiation therapy, nos","pharmaceutical therapy, nos","surgery, nos","chemotherapy","immunotherapy (including vaccines)","radiation, external beam"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.treatments.treatment_type (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.treatments.treatment_or_therapy","harmonized_name":"diagnoses.treatments.treatment_or_therapy","label":"Treatment given","category":"treatment","n_nonmissing":408,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":99.0,"is_repeated":true,"example_values":["no","yes","unknown"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.treatments.treatment_or_therapy (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.treatments.therapeutic_agents","harmonized_name":"diagnoses.treatments.therapeutic_agents","label":"Therapeutic agents","category":"treatment","n_nonmissing":136,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":33.0,"is_repeated":true,"example_values":["cisplatin","gemcitabine","bcg solution","carboplatin","methotrexate","vinblastine"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.treatments.therapeutic_agents (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.treatments.treatment_outcome","harmonized_name":"diagnoses.treatments.treatment_outcome","label":"Treatment outcome","category":"treatment","n_nonmissing":149,"n_not_reported":19,"n_informative":130,"n_total":412,"coverage_pct":31.6,"populated_pct":36.2,"is_repeated":false,"example_values":["complete response","progressive disease","partial response","unknown","stable disease","treatment ongoing"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.treatments.treatment_outcome","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"diagnoses.treatments.regimen_or_line_of_therapy","harmonized_name":"diagnoses.treatments.regimen_or_line_of_therapy","label":"Regimen or line of therapy","category":"treatment","n_nonmissing":0,"n_not_reported":0,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.0,"is_repeated":false,"example_values":[],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: diagnoses.treatments.regimen_or_line_of_therapy","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"follow_ups.disease_response","harmonized_name":"follow_ups.disease_response","label":"Disease response at follow-up","category":"followup","n_nonmissing":409,"n_not_reported":null,"n_informative":null,"n_total":412,"coverage_pct":null,"populated_pct":99.3,"is_repeated":true,"example_values":["tf-tumor free","wt-with tumor","unknown"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: follow_ups.disease_response (one-to-many; counts are per record)","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"follow_ups.progression_or_recurrence","harmonized_name":"follow_ups.progression_or_recurrence","label":"Progression at follow-up","category":"followup","n_nonmissing":143,"n_not_reported":0,"n_informative":143,"n_total":412,"coverage_pct":34.7,"populated_pct":34.7,"is_repeated":false,"example_values":["yes"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: follow_ups.progression_or_recurrence","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"follow_ups.ecog_performance_status","harmonized_name":"follow_ups.ecog_performance_status","label":"ECOG performance status","category":"followup","n_nonmissing":128,"n_not_reported":27,"n_informative":101,"n_total":412,"coverage_pct":24.5,"populated_pct":31.1,"is_repeated":false,"example_values":["1","0","unknown","2","3","4"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: follow_ups.ecog_performance_status","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"exposures.tobacco_smoking_status","harmonized_name":"exposures.tobacco_smoking_status","label":"Tobacco smoking status","category":"exposure","n_nonmissing":411,"n_not_reported":13,"n_informative":398,"n_total":412,"coverage_pct":96.6,"populated_pct":99.8,"is_repeated":false,"example_values":["current reformed smoker for > 15 yrs","lifelong non-smoker","current smoker","current reformed smoker for < or = 15 yrs","current reformed smoker, duration not specified","unknown"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: exposures.tobacco_smoking_status","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},{"name":"exposures.alcohol_history","harmonized_name":"exposures.alcohol_history","label":"Alcohol history","category":"exposure","n_nonmissing":1,"n_not_reported":1,"n_informative":0,"n_total":412,"coverage_pct":0.0,"populated_pct":0.2,"is_repeated":false,"example_values":["not reported"],"unit":null,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&facets=demographic.sex_at_birth%2Cdemographic.race%2Cdemographic.ethnicity%2Cdemographic.vital_status%2Cdemographic.cause_of_death%2Cdemographic.population_group%2Cdemographic.country_of_residence_at_enrollment%2Cdiagnoses.primary_diagnosis%2Cdiagnoses.morphology%2Cdiagnoses.tissue_or_organ_of_origin%2Cdiagnoses.ajcc_pathologic_stage%2Cdiagnoses.ajcc_clinical_stage%2Cdiagnoses.tumor_grade%2Cdiagnoses.prior_treatment%2Cdiagnoses.prior_malignancy%2Cdiagnoses.synchronous_malignancy%2Cdiagnoses.progression_or_recurrence%2Cdiagnoses.last_known_disease_status%2Cdiagnoses.classification_of_tumor%2Cdiagnoses.treatments.treatment_type%2Cdiagnoses.treatments.treatment_or_therapy%2Cdiagnoses.treatments.therapeutic_agents%2Cdiagnoses.treatments.treatment_outcome%2Cdiagnoses.treatments.regimen_or_line_of_therapy%2Cfollow_ups.disease_response%2Cfollow_ups.progression_or_recurrence%2Cfollow_ups.ecog_performance_status%2Cexposures.tobacco_smoking_status%2Cexposures.alcohol_history&size=0","source_label":"GDC API /cases facets","retrieved_at":"2026-09-18T02:36:28.281436Z","snippet":null,"locator":"facet: exposures.alcohol_history","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]}],"longitudinal":{"has_followup":true,"has_survival_endpoint":true,"survival_endpoints":["overall survival","progression-free interval"],"median_followup_months":17.5,"max_followup_months":165.9,"n_cases_with_followup":411,"has_serial_samples":true,"timepoints":[],"n_cases_with_serial":410,"has_treatment_response":true,"response_criteria":["complete response","partial response","progressive disease","stable disease","treatment ongoing"],"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/cases?filters=%7B%22content%22%3A+%7B%22field%22%3A+%22project.project_id%22%2C+%22value%22%3A+%5B%22TCGA-BLCA%22%5D%7D%2C+%22op%22%3A+%22in%22%7D&fields=diagnoses.age_at_diagnosis%2Cdiagnoses.days_to_last_follow_up%2Cdiagnoses.days_to_recurrence%2Cdemographic.days_to_death%2Cdemographic.vital_status%2Cfollow_ups.days_to_follow_up%2Cfollow_ups.days_to_progression%2Cdiagnoses.treatments.days_to_treatment_start&size=412&format=json","source_label":"GDC API /cases (case-level fields)","retrieved_at":"2026-09-18T02:36:29.750034Z","snippet":null,"locator":"computed from 412 cases; follow-up time derivable for 411 of them","confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},"access":{"tier":"mixed","open_components":["10,603 open-access files"],"controlled_components":["20,899 controlled-access files"],"mechanism":"Data Access Request through dbGaP using an eRA Commons account; institutional signing official approval required","dua_url":"https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000178","data_access_committee":"NCI Data Access Committee","typical_turnaround":"days to a few weeks after signing official approval","embargo_until":null,"login_required":true,"citation_requirement":"Cite the dataset accession and the program's publication guidelines; see the GDC publication policy.","license":"NIH Genomic Data Sharing Policy terms","publication_policy_url":"https://gdc.cancer.gov/about-data/publications","evidence":[{"method":"api","source_url":"https://api.imaging.datacommons.cancer.gov/v3/collections/tcga_blca","source_label":"IDC v3 API /collections","retrieved_at":"2026-09-18T02:44:36.389375Z","snippet":null,"locator":null,"confidence":"high","reviewer":null,"reviewed_at":null,"note":null}]},"useful_for":[],"limitations":[],"inappropriate_uses":[],"primary_publications":[{"pmid":"24476821","pmcid":null,"doi":null,"title":"Comprehensive molecular characterization of urothelial bladder carcinoma","journal":"Nature","year":2014,"authors_short":null,"n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/24476821/","is_open_access":null,"citation_count":null,"evidence":[{"method":"curated","source_url":"https://pubmed.ncbi.nlm.nih.gov/24476821/","source_label":"Marker paper (curated registry)","retrieved_at":"2026-09-21T12:30:56.916769Z","snippet":null,"locator":"marker paper for gdc-tcga-blca","confidence":"high","reviewer":"CD2S project curation","reviewed_at":"2026-09-20","note":"Named by a reviewer as the publication that describes this cohort and reports its data generation, and verified against Europe PMC by title, journal and year. This is what the dataset's citation count counts citations to, and the only thing a generation award is attributed from."}]}],"reuse":[{"publication":{"pmid":"41496642","pmcid":"PMC12779901","doi":"10.1177/15579883251410519","title":"Harnessing Ubiquitin-Proteasome System-Related Genes to Identify Subtypes of Bladder Cancer and Reveal Immune Landscape.","journal":"American journal of men's health","year":2026,"authors_short":"Shi et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/41496642/","is_open_access":true,"citation_count":1,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["shi g","wang t","yang f","zhou x"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"42164352","pmcid":"PMC13184252","doi":"10.21037/tau-2025-1-936","title":"DARS2 serves as an independent prognostic factor and participates in multiple biological processes in bladder urothelial carcinoma.","journal":"Translational andrology and urology","year":2026,"authors_short":"Qiu et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/42164352/","is_open_access":true,"citation_count":1,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["deng c","deng s","deng z","dong l","guo c","lin t","qiu r"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"40973873","pmcid":"PMC13032880","doi":"10.1093/jmcb/mjaf032","title":"The tumor-associated fibroblasts regulate urothelial carcinoma progression.","journal":"Journal of molecular cell biology","year":2026,"authors_short":"Xiao et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/40973873/","is_open_access":true,"citation_count":1,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["huang f","kang l","leng j","liu q","luo c","sun m","wang j","xiao y","yang c","yang j","yang m","zhang c"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"41006616","pmcid":"PMC12475427","doi":"10.1038/s41598-025-18820-2","title":"Identification of biomarkers associated with mitophagy in bladder cancer.","journal":"Scientific reports","year":2025,"authors_short":"Huang et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/41006616/","is_open_access":true,"citation_count":1,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["huang x","meng y","peng x","song j","xiong y","zhu y"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"41298892","pmcid":"PMC12748658","doi":"10.1038/s41698-025-01195-y","title":"Bladder cancer diagnostic and prognostic models from DNA methylation by multi algorithm machine learning.","journal":"NPJ precision oncology","year":2025,"authors_short":"Shen et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/41298892/","is_open_access":true,"citation_count":1,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["ding g","shen j","wang r","zhang y"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"42649617","pmcid":"PMC13519135","doi":"10.1111/iju.70609","title":"Cathepsin V (CTSV) Shapes the Epigenetic-Immune Landscape of Bladder Cancer and Emerges as a Noninvasive Biomarker.","journal":"International journal of urology : official journal of the Japanese Urological Association","year":2026,"authors_short":"Ferreira et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/42649617/","is_open_access":true,"citation_count":0,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["ferreira w","marchi f","oliveira e","rodrigues a","villacis r","vitiello g"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"42373686","pmcid":"PMC13315911","doi":"10.1038/s41598-026-54966-3","title":"Integrating whole-genome bisulfite sequencing and TCGA data reveals methylation patterns associated with the MTHFR 677 C > T Variant.","journal":"Scientific reports","year":2026,"authors_short":"Zhang et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/42373686/","is_open_access":true,"citation_count":0,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"DATA_AVAILABILITY, METHODS","author_keys":["dong z","gao x","guo m","hou j","jiamingyan","wang z","yang r","zhang g"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DATA_AVAILABILITY:\"TCGA-BLCA\"","source_label":"Europe PMC section search (DATA_AVAILABILITY)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in DATA_AVAILABILITY","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"41870815","pmcid":"PMC13133299","doi":"10.1007/s12672-026-04851-2","title":"Construction and evaluation of a bladder cancer prognosis model based on super-enhancer-associated genes.","journal":"Discover oncology","year":2026,"authors_short":"Xu et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/41870815/","is_open_access":true,"citation_count":0,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"DATA_AVAILABILITY, METHODS","author_keys":["zeng t","zeng z","zhu z","zou x"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DATA_AVAILABILITY:\"TCGA-BLCA\"","source_label":"Europe PMC section search (DATA_AVAILABILITY)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in DATA_AVAILABILITY","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"42459315","pmcid":"PMC13369512","doi":"10.3389/fonc.2026.1784832","title":"Identification of key genes potentially associated with bladder cancer development by common plasticizers: an integrated transcriptomics and network toxicology study.","journal":"Frontiers in oncology","year":2026,"authors_short":"Zhang et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/42459315/","is_open_access":true,"citation_count":0,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["chen z","zhang q","zhao d"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]},{"publication":{"pmid":"42436777","pmcid":"PMC13355264","doi":"10.21037/tau-2026-0327","title":"Identification of pyroptosis-related molecular subtypes and development of a subtype-derived six-gene prognostic signature for bladder cancer.","journal":"Translational andrology and urology","year":2026,"authors_short":"Tang et al.","n_authors":null,"url":"https://pubmed.ncbi.nlm.nih.gov/42436777/","is_open_access":true,"citation_count":0,"evidence":[]},"tier":"t3_analyzed","kind":"secondary_analysis","independent_of_generators":true,"what_they_analyzed":null,"what_they_found":null,"methods_summary":null,"modalities_used":[],"accession_snippet":null,"accession_locator":"METHODS","author_keys":["chen f","tang s","wang x","zhang l","zhang m"],"nci_funded_reuse":false,"linked_grants":[],"adjudicated_by":null,"adjudicated_at":null,"evidence":[{"method":"fulltext","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=METHODS:\"TCGA-BLCA\"","source_label":"Europe PMC section search (METHODS)","retrieved_at":"2026-09-18T03:19:09.283474Z","snippet":null,"locator":"accession \"TCGA-BLCA\" indexed in METHODS","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Search strategy epmc-sectioned-v1. Section placement is used to grade the strength of reuse evidence, not merely to confirm a citation."}]}],"reuse_metrics":{"n_candidates_screened":894,"n_by_tier":{"t3_analyzed":894,"t2_declared":112,"t1_accession":0,"t0_mention":104},"n_by_tier_raw":{"t3_analyzed":925,"t2_declared":116,"t1_accession":0,"t0_mention":108},"accession_precision":{"token":"TCGA-BLCA","query":"METHODS:\"TCGA-BLCA\"","strategy_id":"epmc-literal-precision-v1","needs_correction":true,"precision":0.9667,"precision_low":0.8333,"precision_high":0.9941,"n_sampled":30,"n_checked":30,"n_literal":29,"note":"29 of 30 sampled open-access articles contain the literal accession TCGA-BLCA; the rest match only because Europe PMC indexes the hyphen as a word break. Counts for this dataset are scaled by 97% accordingly."},"n_citations_to_primary_publication":2361,"citation_to_reuse_ratio":2.6,"has_citable_accession":true,"n_verified_reuse":894,"n_reuse_examined":111,"n_independent_reuse":10,"n_nci_funded_reuse":0,"first_reuse_year":2025,"latest_reuse_year":2026,"years_since_release":12.72,"expected_reuse":247.0,"reuse_gap_index":1.852,"reuse_gap_percentile":90.2,"search_strategy_id":"epmc-index-v3","searched_at":"2026-09-20T18:07:31.339936Z","no_reuse_identified":false,"evidence":[{"method":"derived","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search","source_label":"Europe PMC section-scoped hit counts","retrieved_at":"2026-09-20T18:07:31.339936Z","snippet":null,"locator":"tokens: TCGA-BLCA; queries: METHODS:\"TCGA-BLCA\"; DATA_AVAILABILITY:\"TCGA-BLCA\"; ACCESSION_ID:\"TCGA-BLCA\"; INTRO:\"TCGA-BLCA\"","confidence":"high","reviewer":null,"reviewed_at":null,"note":"Index strategy epmc-index-v3. Every dataset is measured with the same single section field per tier, so the counts are comparable; the per-tier value is the largest across the dataset's own accessions, excluding any accession shared with other datasets in the corpus. 29 of 30 sampled open-access articles contain the literal accession TCGA-BLCA; the rest match only because Europe PMC indexes the hyphen as a word break. Counts for this dataset are scaled by 97% accordingly."},{"method":"derived","source_url":"https://www.ebi.ac.uk/europepmc/webservices/rest/search","source_label":"Europe PMC first-reference dating","retrieved_at":"2026-09-20T18:10:45.163052Z","snippet":null,"locator":"first referenced in 2014 (METHODS section)","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Availability dated from the literature (epmc-first-reference-v2) rather than from repository file timestamps, which record re-harmonization. This is a lower bound on availability."}]},"underexplored":{"is_underexplored":false,"basis":["Reuse is within the expected range for comparable datasets (index +1.85)."],"index_value":1.852,"percentile":90.2,"comparator_set":"132 datasets in this corpus with a citable accession and sufficient metadata","evidence":[{"method":"derived","source_url":null,"source_label":"Reuse Gap Index (rgi-huber-v2)","retrieved_at":"2026-09-21T02:11:22.976067Z","snippet":null,"locator":"Huber robust regression of log2(analyzing articles + 1) on cohort size, years available, modality breadth and access tier","confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Model, covariates and coefficients are published with the dataset export so the label can be recomputed or contested."}]},"grants":[{"core_project_num":"U24CA180951","project_num":null,"title":"Cloud Based Resource for Data Hosting, Visualization and Analysis Using UCSC Canc","pi_names":["DAVID H HAUSSLER"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2013,2014,2015,2016,2017],"award_amount_usd":2939697,"org_name":"UNIVERSITY OF CALIFORNIA SANTA CRUZ","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA180951","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA180951","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA144025","project_num":null,"title":"Harvard Genome Characterization Center","pi_names":["Raju S. Kucherlapati"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":13968228,"org_name":"BRIGHAM AND WOMEN'S HOSPITAL","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA144025","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA144025","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143883","project_num":null,"title":"Integrative Pipeline for Analysis & Translational Application of TCGA Data (GDAC)","pi_names":["Rehan Akbani","GORDON B. MILLS","John N Weinstein","W K ALFRED Yung"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":10635408,"org_name":"UNIVERSITY OF TX MD ANDERSON CAN CTR","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143883","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143883","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143882","project_num":null,"title":"The USC-JHU Cancer Epigenome Characterization Center","pi_names":["STEPHEN B. BAYLIN","Daniel Joseph Weisenberger","PETER W LAIRD"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":13289758,"org_name":"UNIVERSITY OF SOUTHERN CALIFORNIA","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143882","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143882","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143867","project_num":null,"title":"Genome Characterization Center (GCC)","pi_names":["Stacey Gabriel","Matthew L. Meyerson"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2015,2016],"award_amount_usd":16983070,"org_name":"BROAD INSTITUTE, INC.","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143867","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143867","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143866","project_num":null,"title":"Cancer transcriptome characterization using massively parallel DNA sequencing","pi_names":["Marco Antonio Marra"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2015],"award_amount_usd":10876224,"org_name":"BRITISH COLUMBIA CANCER AGENCY","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143866","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143866","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143858","project_num":null,"title":"UCSC-Buck Inst. Genome Data Analysis Center for TCGA Research Network (GDAC)","pi_names":["Christopher Benz","DAVID H HAUSSLER"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":8873081,"org_name":"UNIVERSITY OF CALIFORNIA SANTA CRUZ","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143858","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143858","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143848","project_num":null,"title":"Gene Expression Patterns in Human Tumors Identified Using Transcript Sequencing","pi_names":["David N Hayes","CHARLES M PEROU"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":20842970,"org_name":"UNIV OF NORTH CAROLINA CHAPEL HILL","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143848","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143848","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143845","project_num":null,"title":"The Cancer Genome Atlas Data Analysis Center","pi_names":["LYNDA CHIN","GAD A GETZ"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":15987999,"org_name":"BROAD INSTITUTE, INC.","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143845","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143845","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143843","project_num":null,"title":"The BCM Tumor Genome Characterization Center","pi_names":["RICHARD A GIBBS","David Andrew Wheeler"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013],"award_amount_usd":9488061,"org_name":"BAYLOR COLLEGE OF MEDICINE","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143843","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143843","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143840","project_num":null,"title":"MSKCC Center for Translational Cancer Genomic Analysis","pi_names":["Marc Ladanyi","CHRIS SANDER"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":11508790,"org_name":"SLOAN-KETTERING INST CAN RESEARCH","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143840","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143840","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143835","project_num":null,"title":"Center for Systems Analysis of the Cancer Regulome","pi_names":["ILYA SHMULEVICH"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":10612504,"org_name":"INSTITUTE FOR SYSTEMS BIOLOGY","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143835","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143835","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA143799","project_num":null,"title":"TCGA Data Analysis Center at Berkeley","pi_names":["PAUL T. SPELLMAN","Terence Paul Speed"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2009,2010,2011,2012,2013,2014,2016],"award_amount_usd":4897945,"org_name":"OREGON HEALTH & SCIENCE UNIVERSITY","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA143799","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA143799","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"U24CA126554","project_num":null,"title":"Cancer Genomics Center","pi_names":["Raju S. Kucherlapati"],"agency_ic":"CA","activity_code":"U24","fiscal_years":[2006,2007,2008,2009],"award_amount_usd":6095365,"org_name":"BRIGHAM AND WOMEN'S HOSPITAL","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=U24CA126554","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under U24CA126554","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]},{"core_project_num":"P30CA016672","project_num":null,"title":"Cancer Center Support Grant","pi_names":["PETER W PISTERS","FUNDA MERIC-BERNSTAM","Shannon Neville Westin","Kristy Brock","Vicki Huff","Fernando J Benavides","Giulio Francesco Draetta","Elizabeth J Shpall","Ignacio I. Wistuba","Dihua Yu","Wendy A Woodward","RICHARD D WOOD","J. Jack LEE","JOHN D. HAZLE","Laura del Carmen Bover","Vanessa Jensen","YILING LU","Eduardo Vilar Sanchez","ANIL K SOOD","DIANE BODURKA","Susan K Peterson","Jian Hu","Shreya Kanodia","Scott Kopetz","ROBERT ZYGMUNT ORLOWSKI","VINAY K PUDUVALLI","Christopher J. Logothetis","John N Weinstein","Ernest T. Hawk","STEPHEN Y LAI","John V. Heymach","Paul A Scheet","David S. Hong","Jennifer Keating Litton","JAMES P ALLISON","MICHAEL ANDREEFF","POWEL H BROWN","Jeffrey Nicholas Myers","Xiaodong Cheng","Karen Hsieh Lu","Lorenzo Cohen","Robert Langley","Jan Parker-Thornburg","ROBERT C BAST","KELLY K HUNT","ALBERT KOONG","Filip Janku","WILLIAM K PLUNKETT","Alan McClelland","Amy Beth Heimberger","SHARON Y. R. DENT","Michelle Ann Barton","GUILLERMINA LOZANO","Aman U Buzdar","MIEN-CHIE HUNG","RICHARD E. CHAMPLIN"],"agency_ic":"NCI","activity_code":"P30","fiscal_years":[2019,2020,2021,2022,2023,2024,2025],"award_amount_usd":163861036,"org_name":"UNIVERSITY OF TX MD ANDERSON CAN CTR","reporter_url":"https://reporter.nih.gov/search/results?text_criteria=P30CA016672","role":"generation","evidence":[{"method":"api","source_url":"https://api.reporter.nih.gov/v2/publications/search","source_label":"NIH RePORTER","retrieved_at":"2026-09-20T17:21:14.041075Z","snippet":null,"locator":"PMID 24476821 (this dataset's marker paper) reported under P30CA016672","confidence":"high","reviewer":null,"reviewed_at":null,"note":"The award is credited on the dataset's own marker paper, so it paid to produce these data rather than to analyse them. Resolved from RePORTER's publication index; only a repository-supplied or reviewer-supplied marker paper is used, never one this pipeline nominated itself."}]}],"access_steps":[{"order":1,"action":"Open the project in the GDC Data Portal","detail":"Check the portal's current case and file counts before requesting anything; the cohort can change after this record was built.","url":"https://portal.gdc.cancer.gov/projects/TCGA-BLCA","requires":[],"est_time":"5 minutes","cli_snippet":null,"audience":"human","evidence":[{"method":"derived","source_url":"https://portal.gdc.cancer.gov/projects/TCGA-BLCA","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430171Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]},{"order":2,"action":"Download the open files without an account","detail":"10,603 open-access files are marked open access. Add them to a portal cart, export a manifest, and fetch it with the GDC Data Transfer Tool.","url":"https://gdc.cancer.gov/access-data/gdc-data-transfer-tool","requires":[],"est_time":"minutes to hours, by cohort size","cli_snippet":"gdc-client download -m gdc_manifest.txt","audience":"human","evidence":[{"method":"derived","source_url":"https://gdc.cancer.gov/access-data/gdc-data-transfer-tool","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430174Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]},{"order":3,"action":"Request controlled access through dbGaP","detail":"20,899 controlled-access files require an approved data access request. The request starts at dbGaP, not in the portal. The relevant study is phs000178.","url":"https://gdc.cancer.gov/access-data/obtaining-access-controlled-data","requires":["eRA Commons account","institutional signing official approval","dbGaP data access request for phs000178"],"est_time":"days to a few weeks after signing official approval","cli_snippet":null,"audience":"human","evidence":[{"method":"derived","source_url":"https://gdc.cancer.gov/access-data/obtaining-access-controlled-data","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430175Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]},{"order":4,"action":"Download controlled files with your token","detail":"An approved request yields a token. The same manifest fetches nothing controlled without it.","url":"https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000178","requires":["approved dbGaP request","GDC authentication token"],"est_time":null,"cli_snippet":"gdc-client download -m gdc_manifest.txt -t gdc-user-token.txt","audience":"human","evidence":[{"method":"derived","source_url":"https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000178","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430178Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]},{"order":5,"action":"Query the project from code, with no credentials","detail":"The file index is public even where files are not, so an agent can size the cohort before anyone requests access.","url":"https://docs.gdc.cancer.gov/API/Users_Guide/Getting_Started/","requires":[],"est_time":null,"cli_snippet":"curl -s 'https://api.gdc.cancer.gov/files' --get \\\n  --data-urlencode 'filters={\"op\":\"in\",\"content\":{\"field\":\"cases.project.project_id\",\"value\":[\"TCGA-BLCA\"]}}' \\\n  --data-urlencode 'fields=file_id,file_name,data_type' \\\n  --data-urlencode 'size=10000' --data-urlencode 'format=TSV'","audience":"agent","evidence":[{"method":"derived","source_url":"https://docs.gdc.cancer.gov/API/Users_Guide/Getting_Started/","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430180Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]},{"order":6,"action":"Pass the token when the agent needs controlled files","detail":"Without a token, an API query may return only the open subset. Compare returned counts with the record before treating them as the whole cohort.","url":"https://docs.gdc.cancer.gov/API/Users_Guide/Getting_Started/","requires":["GDC authentication token"],"est_time":null,"cli_snippet":"curl -H \"X-Auth-Token: $GDC_TOKEN\" https://api.gdc.cancer.gov/data/<file_id>","audience":"agent","evidence":[{"method":"derived","source_url":"https://docs.gdc.cancer.gov/API/Users_Guide/Getting_Started/","source_label":"GDC access documentation","retrieved_at":"2026-09-21T12:30:59.430182Z","snippet":null,"locator":null,"confidence":"medium","reviewer":null,"reviewed_at":null,"note":"Generated by applying the repository's documented access policy to this dataset's identifiers. It is not a reviewer's account of this dataset."}]}],"analysis_examples":[],"agent_package":{"json_url":"/data/datasets/gdc-tcga-blca.json","jsonld_url":"/data/jsonld/gdc-tcga-blca.jsonld","croissant_url":"/data/croissant/gdc-tcga-blca.json","instructions_url":"/data/agent/gdc-tcga-blca.md","bundle_url":null,"mcp_resource_uri":null},"related_dataset_ids":[],"related_underexplored_ids":[],"review":{"status":"machine_only","reviewer":null,"reviewer_affiliation":null,"reviewed_at":null,"sections_reviewed":[],"open_questions":[],"notes":null},"verification":{"last_verified_at":null,"link_checks":[],"n_links_ok":0,"n_links_broken":0,"upstream_version_seen":null,"upstream_version_changed":false,"upstream_counts_seen":{},"upstream_drift":{},"notes":[]},"is_showcase":false,"completeness_score":42.9,"tags":["gdc","has-derived-annotations","idc","imaging","imaging-genomics","imaging-pathology","released","tcga"],"search_text":null}