{"id":"gdc-ctsp-dlbcl1","title":"CTSP Diffuse Large B-Cell Lymphoma (DLBCL) CALGB 50303","short_title":"CTSP-DLBCL1","aliases":["CTSP-DLBCL1"],"summary":"What makes this cohort worth knowing about is not its size but its provenance. The samples come from CALGB 50303, a randomized phase III trial comparing dose-adjusted EPOCH-R against R-CHOP as frontline therapy for diffuse large B-cell lymphoma. Molecular data collected inside a randomized trial are scarce: treatment assignment is not confounded with patient characteristics, which is the assumption that almost every observational treatment-response analysis has to make and cannot verify.\nVital status is informative for 100% of the 45 cases and median follow-up is 60.4 months. RNA sequencing covers 44 cases, exome 44 and a targeted panel all 45.","one_liner":"45 diffuse large B-cell lymphomas from the randomized CALGB 50303 trial - small, but every case has complete vital status, five years of median follow-up, and a known randomized treatment assignment.","identifiers":[{"scheme":"gdc_project_id","value":"CTSP-DLBCL1","url":"https://portal.gdc.cancer.gov/projects/CTSP-DLBCL1","is_primary":true,"evidence":[{"method":"api","source_url":"https://api.gdc.cancer.gov/projects/CTSP-DLBCL1?expand=summary,summary.data_categories,summary.experimental_strategies,program","source_label":"GDC API 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